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Intended Use

This kit is used for qualitative detection of the MTHFR (5,10-methylenetetrahydrofolate reductase) gene C677T polymorphism in the genomic DNA of human oral swab samples, and the oral swab samples can be directly used for detection without nucleic acid extraction.

MTHFR C677T mutation can result in a decrease in heat resistance and enzymatic activity. It leads to folic acid metabolism disorders, which greatly increases the risk of fetal neural tube defects in the first trimester. The test results of this kit provide auxiliary diagnosis for high-risk groups with low activity of MTHFR.

Specifications

Catalog No.: HMGP001

Sample Type: Human oral swab samples

Reaction Volume: 50μL

Storage Conditions and Validity:-20±5℃for 12 months

Sensitivity:2000 copies/mL

Detecting Target:C677T polymorphism site of human MTHFR gene

Detection Channel:

Features

Convenient and Efficient

Rapid judgment of results, better aid in disease diagnosis.

High Sensitivity & High Precision

The sensitivity is 2000 copies/mLand CV≤ 5%.

Strong Compatibility

Suitable for multiple kinds of fluorescent PCR instruments

Safe & Reliable

UsedUTP-UDGenzyme to prevent PCR contamination

Components